RECENT ADVANCES IN THE THERAPEUTIC EFFICACY OF ARTESUNATE

Recent Advances in the Therapeutic Efficacy of Artesunate

Artesunate, a semisynthetic artemisinin derivative, is well-known and used as the first-line drug for treating malaria.Apart from treating malaria, artesunate Frais de dossier has also been found to have biological activity against a variety of cancers and viruses.It also exhibits antidiabetic, anti-inflammatory, anti-atherosclerosis, immunosuppres

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Population-specific haplotype association of the postsynaptic density gene DLG4 with schizophrenia, in family-based association studies.

The post-synaptic density (PSD) of glutamatergic synapses harbors a multitude of proteins critical for maintaining synaptic dynamics.Alteration of protein expression levels in this matrix is a marked phenomenon of Probiotics neuropsychiatric disorders including schizophrenia, where cognitive functions are impaired.To investigate the genetic relatio

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Local-Global Graph Fusion to Enhance scRNA-Seq Clustering

Single-cell RNA sequencing (scRNA-seq) is crucial for demystifying the cell heterogeneity and differentiation processes, enabling the identification of distinct cell subtypes within a population.However, most of the existing approaches are feeble to comprehensively Book investigate the interactive relationships between cells and exploit the topolog

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Inhibiting Type VI Secretion System Activity with a Biomimetic Peptide Designed To Target the Baseplate Wedge Complex

ABSTRACT Human health is threatened by bacterial infections that are increasingly resistant to multiple drugs.A recently emerged strategy consists of disarming pathogenic bacteria by targeting and blocking their virulence factors.The type VI secretion system (T6SS) is a widespread secretion nanomachine encoded and employed by pathogenic strains to

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Mechanistic Rationale and Clinical Efficacy of Hyperbaric Oxygen Therapy in Chronic Neuropathic Pain: An Evidence-Based Narrative Review

Background.Chronic neuropathic pain is a condition affecting an increasing proportion of the general Probiotics population and its management requires a comprehensive, multidisciplinary program.A growing body of evidence supports the use of hyperbaric oxygen therapy (HBOT) in several chronic neuropathic pain conditions; however, its role and effica

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